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Product Type: ORALS
Compositioneach tablet contains: Mesterolone 25mg
Presentation: green 25mg tablets, 100 tablets resealablefoil pouch
Storage: Keep out of the reach of children; protect fromlight; store in a cool dry place; do not refrigerate
Manufacturedby: Hygene Anabolic
Provi – 25 is an orally active, 1-methylated DHT. Like Masteron, but thenactually delivered in an oral fashion. DHT is the conversion product oftestosterone at the 5-alpha-reductase enzyme, the result being a hormone thatis 3 to 4 times as androgenic and is structurally incapable of formingestrogen. One would imagine then that mesterolone would be a perfect drug toenhance strength and add small but completely lean gains to the frame.Unfortunately there is a control mechanism for DHT in the human body. Whenlevels get too high, the 3alpha hydroxysteroid dehydrogenase enzyme converts itto a mostly inactive compound known as 3-alpha(5-alpha-androstan-3alpha,17beta-diol), a prohormone if you will. It can equallyconvert back to DHT by way of the same enzyme when low levels of DHT aredetected. But it means that unless one uses ridiculously high amounts, most ofwhat is administered is quite useless at the height of the androgen receptor inmuscle tissue and thus mesterolone is not particularly suited, if at all, topromote muscle hypertrophy.
Provi – 25 has four distinct uses inthe world of bodybuilding. The first being the result of its structure. It is5-alpha reduced and not capable of forming estrogen, yet it nonetheless has amuch higher affinity for the aromatase enzyme (which converts testosterone toestrogen) than testosterone does. That means in administering it withtestosterone or another aromatizable compound, it prevents estrogen build-upbecause it binds to the aromatase enzyme very strongly, thereby preventingthese steroids from interacting with it and forming estrogen. So Mesteroloneuse has the extreme benefit of reducing estrogenic side-effects and waterretention noted with other steroids, and as such still help to provide mostlylean gains. Its also been suggested that it may actually downgrade the actualestrogen receptor making it doubly effective at reducing circulating estrogenlevels.
The second use is in enhancing thepotency of testosterone. Testosterone in the body at normal physiologicallevels is mostly inactive. As much as 97 or 98 percent of testosterone in thatamount is bound to sex hormone binding globulin (SHBG) and albumin, twoproteins. In such a form testosterone is mostly inactive. But as with thearomatase enzyme, DHT has a higher affinity for these proteins thantestosterone does, so when administered simultaneously the mesterolone willattach to the SHBG and albumin, leaving larger amounts of free testosterone tomediate anabolic activities such as protein synthesis. Another way in which ithelps to increase gains. Its also another part of the equation that makes itineffective on its own, as binding to these proteins too, would render it anon-issue at the androgen receptor.
Thirdly, mesterolone is added inpre-contest phases to increase a distinct hardness and muscle density. Probablydue to its reduction in circulating estrogen, perhaps due to the downregulatingof the estrogen receptor in muscle tissue, it decreases the total waterbuild-up of the body giving its user a much leaner look, and a visual effect ofpossessing “harder” muscles with more cuts and striations. Proviron is oftenused as a last-minute secret by a lot of bodybuilders and both actors andmodels have used it time and again to deliver top shape day in day out, whenneeded. Like the other methylated DHT compound, drostanolone, mesterolone isparticularly potent in achieving this feat.
Lastly Provi – 25 is used during acycle of certain hormones such as nandrolone, with a distinct lack ofandrogenic nature, or perhaps 5-alpha reduced hormones that don’t have the sameaffinities as DHT does. Such compounds, thinking of trenbolone, nandrolone andsuch in particular, have been known to decrease libido. Limiting the athlete toperform sexually being the logical result. DHT plays a key role in this processand is therefore administered in conjunction with such steroids to ease orrelieve this annoying side-effect. Proviron is also commonly prescribed bydoctors to people with low levels of testosterone, or patients with chronicimpotence. Its not perceived as a powerful anabolic, but it gets the job doneequally well if not better than other anabolic steroids making it a favorite inmedical practices due to its lower chance of abuse.
Mesterolone is generally well likednonetheless as it delivers very few side-effects in men. In high doses it cancause some virilization symptoms in women. But because of the high level ofdeactivation and pre-destination in the system (albumin, SHBG, 3bHSD,aromatase) quite a lot of it, if not all simply never reaches the androgenreceptor where it would cause anabolic effects, but also side-effects. So itsrelatively safe. Doses between 25 and 250 mg per day are used with no adverse effects.50 mg per day is usually sufficient to be effective in each of the four caseswe mentioned up above, so going higher really isn’t necessary. Unlike what somesuggest or believe, its not advised that Proviron be used when not used inconjunction with another steroid, as it too is quite suppressive of naturaltestosterone, leading to all sorts of future complications upondiscontinuation. Ranging from loss of libido or erectile dysfunction all theway up to infertility. One would not be aware of such dangers because Provironfulfills most of the functions of normal levels of testosterone.
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